Officially yes, from what I know it can be used with one homebrew title - DSQuake, but hopefully more in the future.

January 05, 2026 - 05:06 UTC

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Im lowkey surprised more homebrew doesnt use it
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The first-party ones were basically useless, but the 3-in-1 carts (RAM, rumble, Slot-2 flashcart) were actually quite nice.
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